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non penicillin antibiotic Ing care in ambulatory medical practices non penicillin antibiotic, sinusitis is the most common diagnosis treated with antibiotics. Objectives We examined whether antibiotics are indicated for acute sinusitis non penicillin antibiotic, and if so non penicillin antibiotic, which antibiotic classes are most effective. Search strategy Relevant studies were identified from searches of MEDLINE and EMABASE in December 2001 non penicillin antibiotic, contacts with pharmaceutical companies and bibliographies of included studies. Selection criteria Randomized trials were eligible that compared antibiotic to control or antibiotics from different classes non penicillin antibiotic, for acute maxillary sinusitis. Additional criteria for inclusion were diagnostic confirmation by radiograph or sinus non penicillin antibiotic.
non penicillin antibiotic aspiration non penicillin antibiotic, outcomes that included clinical cure or improvement non penicillin antibiotic, and a sample size of 30 or more adults. Of 2058 potentially relevant studies non penicillin antibiotic, two or more reviewers identified 49 studies meeting selection criteria. Data collection and analysis Data were extracted independently by two persons and synthesized descriptively. Some data were analyzed quantitatively using a random effects model. Primary outcomes were: a) clinical cure non penicillin antibiotic, and b) clinical cure or improvement. Secondary outcomes were radiographic improvement non penicillin antibiotic, relapse rates non penicillin antibiotic, and dropouts due to adverse effects. Main results Forty-nine trials non penicillin antibiotic, involving 13 non penicillin antibiotic, 660 participants non penicillin antibiotic, evaluated antibiotic treatment for acute maxillary sinusitis. Major comparisons were antibiotic versus control (n of 5); newer non penicillin antibiotic, non-penicillin antibiotic versus penicillin class (n of 10); and amoxicillin-clavulanate versus other extended spectrum antibiotics (n of 17) non penicillin antibiotic, where n is the number of trials. Most trials were conducted in otolaryngology settings. Only 8 trials described adequate allocation and concealment procedures; 20 were double-blind. Compared to control non penicillin antibiotic, penicillin improved clinical cures relative risk (RR) 1.72; 95% CI 1.00 to 2.96 . Treatment with amoxicillin did not significantly improve cure rates (RR 2.06; 95% CI 0.65 to 6.53) but there was significant variability bet.
non penicillin antibiotic for acute maxillary sinusitis. Major comparisons were antibiotic versus control (n of 5); newer non penicillin antibiotic, non-penicillin antibiotic versus penicillin class (n of 10); and amoxicillin-clavulanate versus other extended spectrum antibiotics (n of 17) non penicillin antibiotic, where n is the number of trials. Most trials were conducted in otolaryngology settings. Only 8 trials described adequate allocation and concealment procedures; 20 were double-blind. Compared to control non penicillin antibiotic, penicillin improved clinical cures relative risk (RR) 1.72; 95% CI 1.00 to 2.96 . Treatment with amoxicillin did not significantly improve cure rates (RR 2.06; 95% CI 0.65 to 6.53) but there was significant variability betw.
non penicillin antibiotic 
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